​Our approach is to determine where these cavitation lesions exist, treat them by gently cleaning out the diseased tissue, and then rebuild the bone health using “sticky bone”, your own platelet-rich fibrin (PRF) mixed with a biocompatible bone graft.

A jawbone “cavitation” is an area of under-healed bone often left after an extraction, infection, or trauma where blood flow is poor and the marrow space becomes fatty and inflamed. In the simplest terms, it is a hidden pothole in the jawbone bone that may keep signaling inflammation to the rest of the body. Recent reviews describe this as fatty-degenerative osteonecrosis of the jaw (FDOJ) but is most commonly referred to as “cavitation lesions”. 

Our approach is to determine where these cavitation lesions exist, treat them by gently cleaning out the diseased tissue, and then rebuild the bone health using “sticky bone”, your own platelet-rich fibrin (PRF) mixed with a biocompatible bone graft. PRF concentrates your body’s healing cells and growth factors. It is created using lower-g force centrifugation (per Prof. Shahram Ghanaati’s low-speed concept) which enriches PRF and improves early vascularization. Dr. Rick Miron and colleagues have shown that adding PRF to grafts creates a cohesive “sticky” matrix that enhances graft stability and healing. 

Why this matters to whole-body health: multiple observational studies report that cavitation tissue can overexpress inflammatory messengers, especially the chemokine RANTES/CCL5, linked in the wider medical literature to autoimmune and cancer biology. Some case series describe improvements in systemic symptoms after surgical cleanup of these lesions; however, controlled clinical trials are still limited, so these findings should be viewed as promising but not definitive. 

To support bone regeneration after surgery, we encourage smart nutrition and micronutrient support (e.g., Vitamin D3 with K2 and magnesium) as outlined in Dr. Dominik Nischwitz’s Bone Healing Protocol—tailored to your labs and coordinated with your medical team. 

The “take home” message is that jawbone cavitations may be an underlying health risk that you haven’t considered before. Diagnosing and properly treating cavitations with thorough cleaning protocols followed by PRF-based “sticky bone” follows contemporary biologic principles and may reduce inflammatory burdens for many people. Reach out to us today for help determining if jawbone cavitations may be an issue in your health journey.